Borreliacidal OspC Antibody Response of Canines with Lyme Disease Differs Significantly from That of Humans with Lyme Disease
| Autor: | Krista E. Asp, Steven M. Callister, Ronald F. Schell, Jennifer C. Johnson, Steven D. Lovrich, Rhonda L. La Fleur, Dean A. Jobe |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Microbiology (medical)
Lipoproteins Clinical Biochemistry Immunology Biology Blotting Far-Western Veterinary Immunology Bacterial protein Dogs Lyme disease Bacterial Proteins Antigen medicine Animals Humans Immunology and Allergy Borrelia burgdorferi Antigens Bacterial Lyme Disease bacterial infections and mycoses medicine.disease biology.organism_classification Antibodies Bacterial Virology Antibody response Bacterial Outer Membrane Proteins biology.protein Antibody |
| Zdroj: | Clinical and Vaccine Immunology. 14:635-637 |
| ISSN: | 1556-679X 1556-6811 |
| DOI: | 10.1128/cvi.00431-06 |
| Popis: | Humans reliably produce high concentrations of borreliacidal OspC antibodies specific for the seven C-terminal amino acids shortly after infection with Borrelia burgdorferi . We show that dogs also produce OspC borreliacidal antibodies but that their frequencies, intensities, and antigenicities differ significantly. The findings therefore confirm a major difference between the borreliacidal antibody responses of humans and canines with Lyme disease. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|