ANCA in the diagnosis of neutrophil-mediated inflammation
Autor: | Ladislav Cebecauer, Alexandra Lochmanová, Ivo Lochman, Julius Lupač, Vlastimil Král |
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Rok vydání: | 2010 |
Předmět: |
Inflammation
business.industry Neutrophils Immunology Autoantibody Inflammatory Bowel Diseases Routine practice urologic and male genital diseases medicine.disease respiratory tract diseases Antibodies Antineutrophil Cytoplasmic immune system diseases Terminology as Topic Immunology and Allergy Medicine Humans cardiovascular diseases medicine.symptom skin and connective tissue diseases business Vasculitis Autoantibodies |
Zdroj: | Autoimmunity reviews. 10(6) |
ISSN: | 1873-0183 |
Popis: | Inconsistencies in ANCA (anti-neutrophil cytoplasm autoantibodies) and other NSA (neutrophil-specific autoantibodies) terminology frequently cause incorrect indications, choices, applications and interpretations of ANCA diagnostics in routine practice, except for ANCA-associated vasculitis. A review of the current knowledge and the authors' personal experiences based on routine assessments of ANCA and other NSA are documented and presented. A better understanding of the principles and mechanisms of ANCA and other NSA responses and determination, as well as unification of their terminology could result in improvements in indications, applications and the interpretation of ANCA diagnostics in diseases other than vasculitis, especially in IBD (inflammatory bowel diseases), AILD (autoimmune liver diseases), CTD (connective tissue diseases) and other chronic neutrophil-mediated inflammatory diseases. |
Databáze: | OpenAIRE |
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