Association between Drug Use and In-hospital Outcomes after Infrainguinal Bypass for Peripheral Arterial Occlusive Disease
| Autor: | Satinderjit Locham, Mahmoud B. Malas, Besma Nejim, Hanaa Dakour-Aridi, Manasi Arora |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Time Factors Databases Factual Substance-Related Disorders 030204 cardiovascular system & hematology 030218 nuclear medicine & medical imaging 03 medical and health sciences Peripheral Arterial Disease 0302 clinical medicine Postoperative Complications Risk Factors Internal medicine Medicine Humans Hospital Mortality Hospital Costs Stroke Aged Retrospective Studies business.industry Vasospasm Retrospective cohort study General Medicine Odds ratio Length of Stay Middle Aged medicine.disease United States Substance abuse Treatment Outcome Respiratory failure Concomitant Cohort Surgery Female Cardiology and Cardiovascular Medicine business Vascular Surgical Procedures |
| Zdroj: | Annals of vascular surgery. 58 |
| ISSN: | 1615-5947 |
| Popis: | BACKGROUND Drug abuse may affect lower extremity vessels due to ischemia following intra-arterial injections, vasospasm, arterial and venous pseudoaneurysms, arteriovenous fistulae, vasculitis, and complicated abscesses. Little is known about the outcomes of lower extremity bypass (LEB) for peripheral arterial disease (PAD) in patients with a history of drug abuse disorder. The aim of this study is to evaluate the outcomes of LEB in this patient population. METHODS A retrospective study of the Premier Healthcare Database 2009-2015 was performed. In-hospital complications, mortality, and hospitalization costs were assessed in patients with a history of drug abuse disorder (opioids, cannabis, cocaine, sedatives/hypnotics/anxiolytics, and hallucinogens/methamphetamine/psychoactive drugs) who underwent LEB for PAD. Multivariable logistic and generalized linear models were utilized to study the association between drug use/misuse and in-hospital outcomes after LEB. RESULTS Our cohort included 50,976 patients, of which 967 (2%) had a history of drug abuse disorder on admission. The majority of drugs were cannabis (38.5%), followed by opioids (21.5%) and cocaine (14.5%). Patients with a history of drug use/misuse were significantly at a higher risk of developing complications during their hospital stay (71.9% vs. 64.2%, P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|