Efficacy of Standardized Extract of Bacopa monnieri (Bacognize®) on Cognitive Functions of Medical Students: A Six-Week, Randomized Placebo-Controlled Trial
| Autor: | M. U. R. Naidu, Vijay Thawani, Kunda Gharpure, Navneet Kumar, G. Venkat Ramana, L. G. Abichandani |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Article Subject Placebo-controlled study Placebo Double blind 03 medical and health sciences 0302 clinical medicine medicine Bacopa monnieri Normal range biology Traditional medicine Blood biochemistry business.industry Medical school Cognition lcsh:Other systems of medicine lcsh:RZ201-999 biology.organism_classification 030104 developmental biology Complementary and alternative medicine Physical therapy business 030217 neurology & neurosurgery Research Article |
| Zdroj: | Evidence-based Complementary and Alternative Medicine : eCAM Evidence-Based Complementary and Alternative Medicine, Vol 2016 (2016) |
| ISSN: | 1741-427X |
| DOI: | 10.1155/2016/4103423 |
| Popis: | Rationale.Bacopa monnieri, popularly known as Brahmi, has been traditionally used in Ayurveda since ages for its memory enhancing properties. However, data on placebo-controlled trial ofBacopa monnierion intellectual sample is scarce. Hence this study was planned to evaluate the effect ofBacopa monnierion memory of medical students for six weeks.Objective. To evaluate the efficacy ofBacopa monnierion memory of medical students with six weeks’ administration.Method and Material. This was a randomized double blind placebo-controlled noncrossover, parallel trial. Sixty medical students of either gender from second year of medical school, third term, regular batch, were enrolled from Government Medical College, Nagpur, India. Baseline biochemical and memory tests were done. The participants were randomly divided in two groups to receive either 150 mg of standardized extract ofBacopa monnieri(Bacognize) or matching placebo twice daily for six weeks. All baseline investigations were repeated at the end of the trial. Students were followed up for 15 days after the intervention.Results. Statistically significant improvement was seen in the tests relating to the cognitive functions with use ofBacopa monnieri. Blood biochemistry also showed a significant increase in serum calcium levels (still within normal range). |
| Databáze: | OpenAIRE |
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