Age-Related Differences of Risk Profile and Angiographic Findings in Patients with Coronary Heart Disease
| Autor: | Mohammad Salman, SM Mustafa Zaman, Harisul Hoque, Kmhs Sirajul Haque, Ashraf Uddin Sultan, Abu Siddique, Khurshed Ahmed, Milan Prakash Shrestha |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Acute coronary syndrome
medicine.medical_specialty stable angina Framingham Risk Score business.industry General Arts and Humanities Incidence (epidemiology) lcsh:R lcsh:Medicine medicine.disease acute coronary syndrome Coronary heart disease Diabetes mellitus Internal medicine Right coronary artery medicine.artery medicine Cardiology Population study risk factors Myocardial infarction business Dyslipidemia |
| Zdroj: | Bangabandhu Sheikh Mujib Medical University Journal, Vol 3, Iss 1 (2010) |
| ISSN: | 2224-7750 2074-2908 |
| Popis: | Background: Coronary heart disease (CHD) is a major health problem which imposes a significant burden on health care systems because of high morbidity and mortality. Objectives: To compare the risk factors profile for coronary heart disease in young and old subjects. Methods: Total 100 patients (50 subjects less than 40 years of age and 50 subjects more than 40 years of age) with acute coronary syndrome or stable angina who were undergoing coronary angiogram in the Department of Cardiology, University Cardiac Center, Bangabandhu Sheikh Mujib Medical University Dhaka, from July 2006 to June 2008 were evaluated for the presence coronary artery disease risk factors e.g. hypertension, dyslipidemia and smoking. Results: The mean age of the study population in younger group was (33.0 ± 6.4) years and in older group (52.0±8.6). The male to female ratio in both groups was 4:1. Smokers were more in younger group (70.0% vs. 46.0%) (p = 0.032). Hypertension was less in the younger group (38.0% vs. 58.0%) (p = 0.045). Presence of diabetes was higher in the older age group (34.0% vs. 4.0%) (p = 0.001). Higher incidence of family history of coronary heart disease was in the younger age group. The total cholesterol was higher in older group (182.9 ± 33.1) vs. (171.1 ± 24.8 mg/dl) (p = 0.047). 68% of patients of older group and 38% of younger group had stenosis in left anterior descending artery (p = 0.003). The involvement of left circumflex and right coronary artery in older age group were higher (56% and 66% respectively) than those in younger group (36% and 40% respectively) (p = 0.045 and p = 0.009). Conclusion: Ischemic heart disease in younger adults < 40 years had different risk profile characteristics than older patients. Key words: Coronary heart disease; acute coronary syndrome; stable angina; risk factors. DOI: 10.3329/bsmmuj.v3i1.5508 BSMMU J 2010; 3(1): 13-17 |
| Databáze: | OpenAIRE |
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