Difficult diagnosis and localization of focal nesidioblastosis: clinical implications of 68Gallium-DOTA-D-Phe1-Tyr3-octreotide PET scanning
| Autor: | Jae Ri Kim, Wooil Kwon, Youngmin Han, Jin-Young Jang, Sun Whe Kim, Young Min Cho, Hongbeom Kim, Yong Chan Shin |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Nesidioblastosis Octreotide Case Report medicine.disease_cause Diethylene triamine 030218 nuclear medicine & medical imaging Imaging modalities 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Ga(III)-DOTATOC Medicine DOTA Hyperinsulinemic hypoglycemia medicine.diagnostic_test business.industry Focal hyperplasia medicine.disease chemistry Positron emission tomography 030220 oncology & carcinogenesis Surgery Radiology Positron-emission tomography business medicine.drug |
| Zdroj: | Annals of Surgical Treatment and Research |
| ISSN: | 2288-6796 2288-6575 |
| Popis: | Focal nesidioblastosis is a rare cause of endogenous hyperinsulinemic hypoglycemia in adults. Because it is difficult to localize and detect with current imaging modalities, nesidioblastosis is challenging for biliary-pancreatic surgeons. (68)Gallium-DOTA-D-Phe(1)-Tyr(3)-octreotide PET scanning and (111)indium-pentetreotide diethylene triamine pentaacetic acid octreotide scanning may be superior to conventional imaging modalities in determining the localization of nesidioblastosis. We report the successful surgical treatment of a 54-year-old woman with focal hyperplasia of the islets of Langerhans, who experienced frequent hypoglycemic symptoms and underwent various diagnostic examinations with different results. |
| Databáze: | OpenAIRE |
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