Lithium effects on position learning with exploratory and aversive goal-box conditions

Autor: Garth Hines
Rok vydání: 1985
Předmět:
Zdroj: Pharmacology, biochemistry, and behavior. 22(5)
ISSN: 0091-3057
Popis: Under conflict conditions in which reinforcement occurred within mildly aversive white goal-boxes, the chronic administration of lithium chloride (20 meg/l, in drinking water) to rats, while reducing avoidance of the goal boxes, impaired acquisition of an exploration-reinforced position discrimination. These results were interpreted as supporting the concept that lithium salts reduce the individual's reaction to general environmental stimulation--an effect which may account for its therapeutic action in the treatment of manic disorders.
Databáze: OpenAIRE