T1ρ magnetic resonance imaging value as a potential marker to assess the severity of liver fibrosis: A pilot study
| Autor: | Kengo Tomita, Shigeyoshi Soga, Yohsuke Suyama, Hiroshi Kuwamura, Ryota Hokari, Hiroshi Shinmoto, Wakana Murakami |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Cirrhosis ROI region of interest R895-920 Chronic liver disease Article 030218 nuclear medicine & medical imaging Medical physics. Medical radiology. Nuclear medicine 03 medical and health sciences Liver disease Magnetic resonance imaging 0302 clinical medicine Fibrosis medicine Medical imaging Radiology Nuclear Medicine and imaging MRE magnetic resonance elastography ALBI albumin-bilirubin medicine.diagnostic_test business.industry medicine.disease Magnetic resonance elastography Liver 030220 oncology & carcinogenesis Liver biopsy Diagnostic imaging SWE shear-wave elastography Radiology SD standard deviation SLT spin-lock time business MRI magnetic resonance imaging |
| Zdroj: | European Journal of Radiology Open, Vol 8, Iss, Pp 100321-(2021) European Journal of Radiology Open |
| ISSN: | 2352-0477 |
| DOI: | 10.1016/j.ejro.2021.100321 |
| Popis: | Purpose: Assessment of liver fibrosis is essential for the management of liver disease. Although liver biopsy is the gold-standard modality for the diagnosis of liver fibrosis, it has some limitations. Thus, other methods are required to overcome the disadvantages of a liver biopsy. T1ρ magnetic resonance imaging (MRI) values are potential biomarkers for liver cirrhosis. This study aimed to assess the relationship between T1ρ MRI values and liver fibrosis severity by measuring the correlation between T1ρ values and shear wave elastography (SWE) values, which are routinely used for the diagnosis of liver fibrosis. Methods: T1ρ imaging and SWE values were obtained from four healthy volunteers and 16 patients with chronic liver disease. The regions of interest on MR images were drawn and matched with those of the right liver lobe on SWE images. Results: The mean T1ρ values of the right liver lobe correlated positively with the mean SWE values (Pearson’s correlation coefficient: 0.783; p |
| Databáze: | OpenAIRE |
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