日本内科学会
| Autor: | Tsunako Ikeda, Koji Ishii, Kumi Matsuo, Kazuto Ashizawa, Tetsuya Hara, Midori Yamaguchi, Emi Ryu, Masatsugu Kamada, Haruna Yamashita, Satoru Morishita, Yuya Komatsu |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Continuous infusion
Narcotic Antagonists Breast Neoplasms Case Report 030204 cardiovascular system & hematology Intravenous fentanyl 03 medical and health sciences 0302 clinical medicine Naldemedine Breast cancer opioid-induced-constipation (OIC) Internal Medicine medicine Humans opioid withdrawal syndrome (OWS) Opioid withdrawal business.industry Cancer Cancer Pain General Medicine Middle Aged medicine.disease Naltrexone Substance Withdrawal Syndrome Analgesics Opioid naldemedine Anesthesia Female 030211 gastroenterology & hepatology business Opioid-Induced Constipation Oxycodone medicine.drug Brain metastasis |
| Zdroj: | Internal Medicine |
| ISSN: | 0918-2918 |
| Popis: | Opioid-induced-constipation (OIC) can be treated by naldemedine and other peripherally acting mu-opioid receptor antagonists (PAMORA) via a novel mechanism. We describe the case of a 52-year-old female outpatient who developed OIC while receiving oxycodone for pain due to cancer with multiple bone metastases. Although she did not have brain metastasis, opioid withdrawal syndrome (OWS) developed after taking naldemedine orally. Her Clinical Opiate-Withdrawal Score (COWS) was 19 (moderate symptoms). However, she recovered from OWS on intravenous fentanyl and a continuous infusion of oxycodone. She did not develop OWS thereafter and was discharged two days after recovery. Internal medicine, 59(2), pp.293-296; 2020 |
| Databáze: | OpenAIRE |
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