Assessment of Hematological Factors Involved in Development and Prognosis of Idiopathic Sudden Sensorineural Hearing Loss
| Autor: | İsmail Önder Uysal, Kasım Durmuş, Mansur Doğan, Hatice Terzi, Tuba Doğan Karataş, Emine Elif Altuntaş, Mehmet Şencan |
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| Přispěvatelé: | [Durmus, Kasim -- Karatas, Tuba Dogan -- Dogan, Mansur -- Uysal, Ismail Onder -- Altuntas, Emine Elif] Cumhuriyet Univ, Dept Otolaryngol, Fac Med, TR-58140 Sivas, Turkey -- [Terzi, Hatice -- Sencan, Mehmet] Cumhuriyet Univ, Dept Internal Med, Fac Med, TR-58140 Sivas, Turkey |
| Rok vydání: | 2015 |
| Předmět: |
Blood Glucose
Male Neutrophils sudden hearing loss 030204 cardiovascular system & hematology Gastroenterology Hemoglobins Leukocyte Count 0302 clinical medicine Lymphocytes 030223 otorhinolaryngology Aged 80 and over medicine.diagnostic_test Mean corpuscular hemoglobin concentration Platelet Distribution Width General Medicine Middle Aged Prognosis Treatment Outcome outcome Female medicine.symptom Mean Platelet Volume Adult Blood Platelets medicine.medical_specialty Adolescent Hearing loss Hearing Loss Sensorineural Mean corpuscular hemoglobin 03 medical and health sciences Young Adult Internal medicine medicine Humans Lymphocyte Count Mean platelet volume Aged Retrospective Studies business.industry Platelet Count Case-control study Retrospective cohort study Recovery of Function Hearing Loss Sudden Surgery Otorhinolaryngology Laboratory parameters Case-Control Studies Etiology business prognostic marker Follow-Up Studies |
| Zdroj: | The Journal of craniofacial surgery. 27(1) |
| ISSN: | 1536-3732 |
| Popis: | WOS: 000370076800032 PubMed ID: 26703036 Objective: The aim of this study was to investigate the possible effects of routine hematological parameters on the development and prognosis of idiopathic sudden sensorineural hearing loss in patients applying to our clinic. Study design: A retrospective clinical study. Setting One academic health center from 2008 to 2014. Patients and intervention: One hundred forty patients with sudden hearing loss and 132 healthy controls were included in the present study. Results: Patients having idiopathic sudden sensorineural hearing loss were divided into 2 subgroups based on whether they recovered (complete, partial, and slight recovery) (Group 1; n = 83, 59.3%) or not (Group 2; n = 57, 40.7%) during the follow-up term. Group 1, Group 2, and the controls differed statistically significantly in terms of neutrophil-to-lymphocyte ratio (P = 0.001), platelet-to-lymphocyte ratio (P = 0.001), lymphocytes%(P = 0.001), mean corpuscular hemoglobin (P = 0.019), mean corpuscular hemoglobin concentration (P = 0.015), platelet (P = 0.001), mean platelet volume (P = 0.001), platelet distribution width (P = 0.009), and glucose (P = 0.001). The study groups and the controls did not have any significant difference in terms of other laboratory parameters affecting the prognosis of Idiopathic sudden sensorineural hearing loss. Conclusions: The results the authors obtained showed that laboratory parameters such as lymphocyte, lymphocyte%, platelet, mean platelet volume, platelet distribution width, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, mean corpuscular hemoglobin, and mean corpuscular hemoglobin concentration may be indicative for prognosis and treatment success in groups of patients suffering idiopathic sudden sensorineural hearing loss in whose etiology many factors play a role. |
| Databáze: | OpenAIRE |
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