Optimization of the reversed-phase high-performance liquid chromatographic separation of synthetic estrogenic and progestogenic steroids using the multi-criteria decision making method
| Autor: | Jan Vink, D.A. Doornbos, C.H.P. Bruins, Age K. Smilde |
|---|---|
| Přispěvatelé: | Other departments |
| Jazyk: | angličtina |
| Rok vydání: | 1987 |
| Předmět: |
Chromatography
Chemistry Organic Chemistry Estrogens General Medicine Reversed-phase chromatography Biochemistry High-performance liquid chromatography Analytical Chemistry Multi criteria decision Chromatographic separation Decision making methods Phase composition Phase (matter) Progestins Chromatography High Pressure Liquid |
| Zdroj: | Journal of Chromatography A, 410(1), 1-12. ELSEVIER SCIENCE BV Journal of chromatography, 410(1), 1-12. Elsevier |
| ISSN: | 0021-9673 0378-4347 |
| DOI: | 10.1016/s0021-9673(00)90030-x |
| Popis: | The optimization of the reversed-phase high-performance liquid chromatographic separation of a mixture of ethynylestradiol, desogestrel and three related compounds is described. A procedure is used that allows the prediction of the capacity factors of each individual synthetic steroid, depending on the mobile phase composition. Therefore, complete chromatograms can be predicted and evaluated with the multi-criteria decision making method. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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