Suffocation due to Acute Airway Edema in a Patient with Hereditary Angioedema Highlighted the Need for Urgent Improvements in Treatment Availability in Japan
| Autor: | Hisatsugu Takahara, Satoshi Mano, Daisuke Honda, Yuki Shimizu, Yusuke Suzuki, Hisaki Rinno, Hiroaki Io, Hitoshi Suzuki, Teruo Hidaka, Isao Ohsawa, Masayuki Maiguma, Yasuhiko Tomino |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male Asphyxia 03 medical and health sciences 0302 clinical medicine Japan Edema Internal Medicine Humans Medicine 030212 general & internal medicine Tokyo Facial edema asphyxiation Human C1 inhibitor C1 inhibitor business.industry Severe edema Angioedemas Hereditary HAE General Medicine bacterial infections and mycoses University hospital medicine.disease Cardiopulmonary Resuscitation hereditary angioedema Heart Arrest Airway Obstruction Editorial Jaw 030228 respiratory system Face Accidental Anesthesia Hereditary angioedema plasminogen medicine.symptom business Airway Complement C1 Inhibitor Protein |
| Zdroj: | Internal Medicine |
| ISSN: | 1349-7235 0918-2918 |
| Popis: | A 42-year-old Japanese man with hereditary angioedema suffered accidental trauma to his jaw in Shizuoka Prefecture, Japan, which gradually caused facial edema. Since plasma-derived human C1 inhibitor (pdh C1-INH) was unavailable, he had to be transferred to Juntendo University Hospital in Tokyo. Due to his severe edema, he suffered asphyxiation leading to cardiopulmonary arrest upon arrival. The patient was resuscitated and promptly treated with pdh C1-INH. In Japan, the self-administration of pdh C1-INH is not allowed, and every prefecture does not always possess stocks of pdh C1-INH. This case emphasizes the need for urgent improvements in treatment availability in Japan. |
| Databáze: | OpenAIRE |
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