| Autor: |
Yiming Dong, Xiaowei Li, Wanrong Fu, Xiaoxu Tian, Guangli Guo, Ying Peng, Yafei Zhai, Jiangtao Zhao, Zhongren Ding, Xiaoyan Zhao, Jianzeng Dong |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Stem Cell Research, Vol 58, Iss, Pp 102622-(2022) |
| ISSN: |
1873-5061 |
| Popis: |
A 25-years-old hypertrophic cardiomyopathy male patient donated his peripheral blood mononuclear cells (PBMCs) with heterozygote mutation in theTNNT2 gene. We generated induced pluripotent stem cell (iPSC) with normal karyotypic and expressing NANOG, Lin28, GDF3 and DNMT3. The iPSC line has demonstrated pluripotency by differentiating into three germ layers in vitro. The ZZUNEUi021-A would serve as an in vitro model for loss of TNNT2 function. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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