Social deprivation in patients requiring pelvic exenterative surgery
| Autor: | Peter Coyne, John Beynon, M. D. Evans, M. Davies, Rami Radwan, Dean A. Harris, HG Jones |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Colorectal cancer medicine.medical_treatment 030230 surgery 03 medical and health sciences Postoperative Complications 0302 clinical medicine medicine Humans Survival rate Neoadjuvant therapy Aged Retrospective Studies Aged 80 and over Pelvic exenteration Rectal Neoplasms business.industry Gastroenterology Cancer Retrospective cohort study Length of Stay Middle Aged medicine.disease Neoadjuvant Therapy Pelvic Exenteration Surgery Survival Rate Treatment Outcome Social deprivation Social Isolation Quartile Female 030211 gastroenterology & hepatology business |
| Zdroj: | Colorectal Disease. 18:684-687 |
| ISSN: | 1462-8910 |
| Popis: | Aim Pelvic exenteration is an aggressive operation for locally advanced rectal cancer. Social deprivation has been shown to reduce life expectancy and has been linked to a poorer outcome in patients with colorectal cancer. The aim of this study was to analyse the effect of social deprivation scores on the outcome in these complex patients. Method A retrospective review of all patients undergoing pelvic exenteration for primary rectal cancer between 2006 and 2014 was performed. Deprivation scores were calculated for all patients using the Welsh Index of Multiple Deprivation. Patients were then grouped into quartiles, from Q1 (most deprived) to Q4 (least deprived). The primary outcome measure was 5-year survival. Results In all, 120 patients were included (65 female) with a median age of 64 (31-90) years. No differences between quartiles were identified for neoadjuvant therapy (P = 0.687) or type of exenteration (P = 0.690). The median length of stay was significantly higher in the most deprived groups (Q1-Q2; P = 0.023). There was a significant difference in survival between the groups, with lowest 5-year survival rates (53%) in the most deprived quartile (Q1) (P = 0.015). Conclusion Social deprivation is significantly associated with postoperative length of stay and survival in patients undergoing pelvic exenteration for primary rectal cancer. |
| Databáze: | OpenAIRE |
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