Low prevalence of anti-hepatitis E virus IgG antibodies in Tepehuanos in Mexico

Autor: Verónica Dayali Gutierrez-Martinez, Cosme Alvarado-Esquivel, Antonio Sifuentes-Alvarez, Eda Guadalupe Ramírez-Valles
Rok vydání: 2019
Předmět:
Zdroj: Annals of Hepatology, Vol 19, Iss 2, Pp 186-189 (2020)
ISSN: 1665-2681
Popis: Introduction and objective: The epidemiology of infection with hepatitis E virus (HEV) in Tepehuanos (a Mexican ethnic group living in rural areas) is largely unknown. This study aimed to determine the seroprevalence of and risk factors associated with HEV infection in Tepehuanos in Durango, Mexico, and to compare this seroprevalence with that in non-Tepehuanos. Materials and methods: Through a case–control seroprevalence study, we studied 146 Tepehuanos and 146 age- and gender-matched control subjects of the general population from rural settings. The frequency of anti-HEV IgG antibodies was determined using an enzyme-linked immunoassay. Bivariate and multivariate analyses were used to assess the association between seropositivity and socio-demographic, clinical and behavioral characteristics of the Tepehuanos. Results: IgG antibodies against HEV were found in 5 (3.4%; 95% CI: 1.1–7.8) of 146 Tepehuanos and in 46 (31.5%; 95% CI: 24.1–39.7) of 146 control subjects (OR = 0.01; 95% CI: 0.0007–0.20; P
Databáze: OpenAIRE