The concentration of high molecular weight compounds in interstitial tissue fluid: A study in patients with post-reconstructive leg oedema
| Autor: | H.O. Myhre, Rune Haaverstad, Inge Romslo |
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| Rok vydání: | 1997 |
| Předmět: |
Male
medicine.medical_specialty Lower limb atherosclerosis Urology Arterial Occlusive Diseases Immunoglobulin G Ischemia Albumins Subcutaneous interstitial tissue fluid medicine Humans Protein concentration alpha-Macroglobulins Aged chemistry.chemical_classification Aged 80 and over Medicine(all) Leg biology business.industry Albumin Transferrin Middle Aged Blood proteins Intermittent claudication Surgery Macroglobulin Bypass surgery chemistry biology.protein Leg oedema Female Blister suction technique medicine.symptom Cardiology and Cardiovascular Medicine business Extracellular Space Nephelometry |
| Zdroj: | European Journal of Vascular and Endovascular Surgery. 13(4):355-360 |
| ISSN: | 1078-5884 |
| DOI: | 10.1016/s1078-5884(97)80075-5 |
| Popis: | Objectives:To study whether relative changes in the concentration of different proteins of the subcutaneous interstitial tissue fluid in patients with postreconstructive leg oedema could give information on the integrity of the capillary wall following vascular reconstruction.Materials:Sixteen patients developed ipsilateral leg oedema following femoropopliteal (n = 14) or femorotibial (n = 2) bypass surgery for intermittent claudication (n = 10) or critical lower limb ischaemia (n = 6) caused by obliterating atherosclerosis.Methods:The leg volume increase was measured according to the formula of a truncated cone. The blister suction method was used for sampling of subcutaneous interstitial tissue fluid. The concentration of albumin, transferrin, immunoglobulin G and α2-macroglobulin of serum and blister fluid was measured with nephelometry.Results:Seven days postoperatively the mean leg volume increase was 32% (19.8%) in the operated leg compared to the contralateral side (p |
| Databáze: | OpenAIRE |
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