Acid Hematin Pigmentation of the Cornea in Stillborn Fetuses
| Autor: | Gordon W. Klintworth, Mark W. Scroggs, D. B. Chandler |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Pathology
medicine.medical_specialty Amniotic fluid Heme Biology Stain Pathology and Forensic Medicine Cornea Intrauterine death Fetus medicine Humans Fetal Death reproductive and urinary physiology Fetal death Pigmentation Histological Techniques Infant Newborn Anatomy eye diseases Microscopy Electron Tissue sections medicine.anatomical_structure In utero Pediatrics Perinatology and Child Health Hemin sense organs Electron Probe Microanalysis |
| Zdroj: | Pediatric Pathology. 10:319-333 |
| ISSN: | 0277-0938 |
| DOI: | 10.3109/15513819009067121 |
| Popis: | During the postmortem histopathologic evaluation of eyes from stillborn fetuses we noted the presence of a prominent undescribed corneal pigment in 18 of 55 stillborn fetuses. The corneal pigment was frequently associated with documented meconium-stained amniotic fluid, and in no instance was a stained cornea coupled with recorded clear amniotic fluid. Pigmented corneas came from stillborn fetuses with a longer duration of intrauterine death than nonstained corneas. The pigment stained black with the Fontana-Masson stain, was birefringent, and treatment of tissue sections with 5% potassium permanganate and 5% oxalic acid as well as with saturated alcoholic picric acid solution removed the pigment indicating that it is acid hematin. The most likely cause of the acid hematin-stained corneas was tissue acidity created in utero with prolonged intrauterine death. |
| Databáze: | OpenAIRE |
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