Assessing temporal and geographic contacts across the Adriatic Sea through the analysis of genome-wide data from Southern Italy

Autor: Alessandro Raveane, Ludovica Molinaro, Serena Aneli, Marco Rosario Capodiferro, Luciana de Gennaro, Linda Ongaro, Nicola Rambaldi Migliore, Sara Soffiati, Teodoro Scarano, Antonio Torroni, Alessandro Achilli, Mario Ventura, Luca Pagani, Cristian Capelli, Anna Olivieri, Francesco Bertolini, Ornella Semino, Francesco Montinaro
Rok vydání: 2022
Předmět:
Zdroj: Genomics. 114:110405
ISSN: 0888-7543
Popis: Southern Italy was characterised by a complex prehistory that started with different Palaeolithic cultures, later followed by the Neolithization and the demic dispersal from the Pontic-Caspian Steppe during the Bronze Age. Archaeological and historical evidences point to a link between Southern Italians and the Balkans still present in modern times. To shed light on these dynamics, we analysed around 700 South Mediterranean genomes combined with informative ancient DNAs. Our findings revealed high affinities of South-Eastern Italians with modern Eastern Peloponnesians, and a closer affinity of ancient Greek genomes with those from specific regions of South Italy than modern Greek genomes. The higher similarity could be associated with a Bronze Age component ultimately originating from the Caucasus with high Iranian and Anatolian Neolithic ancestries. Furthermore, extremely differentiated allele frequencies among Northern and Southern Italy revealed putatively adapted SNPs in genes involved in alcohol metabolism, nevi features and immunological traits.
Databáze: OpenAIRE