Treatment of substance use disorders in schizophrenia
| Autor: | Lauren T. Catalano, Kristen Bradshaw, Melanie E. Bennett |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Alcohol Drinking Substance-Related Disorders Schizophrenia (object-oriented programming) Psychological intervention Medicine (miscellaneous) behavioral disciplines and activities law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial law Intervention (counseling) mental disorders medicine Humans Psychiatry Craving Randomized Controlled Trials as Topic Cognitive Behavioral Therapy 030227 psychiatry Psychiatry and Mental health Clinical Psychology Alcoholism Diagnosis Dual (Psychiatry) Schizophrenia Psychopharmacology Open label Substance use Psychology Psychosocial 030217 neurology & neurosurgery Clinical psychology Antipsychotic Agents |
| Zdroj: | The American journal of drug and alcohol abuse. 43(4) |
| ISSN: | 1097-9891 |
| Popis: | Substance use disorders (SUDs) represent a great barrier to functional recovery for individuals with schizophrenia. It is important to use research on treatment of SUDs in schizophrenia to guide treatment recommendations and program planning.We review studies of pharmacological and psychosocial interventions to treat SUDs in individuals with schizophrenia.The criteria used to select studies for inclusion are (1) the percentage of the sample with a schizophrenia spectrum diagnosis is at least 25%; (2) participants have a comorbid SUD or problem use of substances; (3) an intervention for SUD is provided; (4) a substance use-related outcome is measured; and (5) the study design enabled examination of pre-post outcome measures including open label trials, nonrandomized evaluations (quasi-experimental designs, nonrandom assignment to groups), or randomized controlled trials.There are few psychopharmacology outcomes studies. Most have examined use of antipsychotic medications to treat SUDs in schizophrenia. Several trials have yielded positive findings for naltrexone in reducing drinking compared to placebo in this population. Motivational and cognitive-behavioral interventions are associated with decreased substance use in several trials.Treatment for SUDs is feasible within a range of settings and acceptable to many individuals with schizophrenia. All individuals with schizophrenia should be offered brief or more extended psychosocial interventions that incorporate discussion of personal reasons to change and training in cognitive-behavioral strategies to reduce use, cope with cravings and stress, and avoid relapse. Future research must include larger samples, longitudinal designs, and similar outcome measures across studies. |
| Databáze: | OpenAIRE |
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