Prevalence and risk factor analysis for HIV/HTLV 1/2 coinfection in Paraíba state, Brazil
| Autor: | Juliana Prado Gonçales, José Valter Joaquim Silva Júnior, Joanne Elizabeth Ferraz da Costa, Maria Rosângela Cunha Duarte Coêlho, Marcela Souza, Thaísa Regina Rocha Lopes, Viviane Martha Santos deMorais |
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| Rok vydání: | 2021 |
| Předmět: |
Male
viruses HIV Infections Microbiology Virus Serology Acquired immunodeficiency syndrome (AIDS) Risk Factors immune system diseases hemic and lymphatic diseases Virology Prevalence Humans Medicine Risk factor biology Coinfection business.industry virus diseases General Medicine medicine.disease HTLV-I Infections Cross-Sectional Studies Infectious Diseases biology.protein Female Parasitology HTLV-1 Infection Antibody business Viral load Brazil |
| Zdroj: | The Journal of Infection in Developing Countries. 15:1551-1554 |
| ISSN: | 1972-2680 |
| Popis: | Introduction: Human T-lymphotropic virus (HTLV) 1 and 2 infections can lead to neurological diseases, mainly in HIV/HTLV 1 coinfected. Furthermore, HTLV 1 infection in HIV/AIDS patients has also been associated with AIDS progression. Despite this, HTLV 1/2 infections are not of mandatory notification in Brazil. Here, we describe the prevalence of HTLV 1/2 in HIV/AIDS patients from Paraíba state, Brazil, as well as the sociodemographic characteristics of the coinfected individuals. Methodology: Information about HIV viral load and TCD4 lymphocyte count were obtained from patients’ records. Data on the patients’ sociodemographic characteristics were obtained by interview conducted after signing the informed consent form. The serological diagnosis for HTLV 1/2 was performed by Enzyme-Linked Immunosorbent Assay (ELISA) and Western Blot (WB). Results: A total of 401 HIV/AIDS patients participated in the study, of whom about 1.5% (6/401) were positive for antibodies against HTLV, specifically for HTLV 1, evaluated by both ELISA and WB. No risk factors were found associated with HIV/HTLV 1/2 coinfection. Conclusions: We report a 1.5% prevalence of HTLV 1 infection in HIV/AIDS patients from Paraíba state. Although we have not identified risk factors associated with HTLV 1, we describe the most observed sociodemographic characteristics in HIV/HTLV 1 coinfection. |
| Databáze: | OpenAIRE |
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