Basal haemoglobin levels as prognostic factor for early death in elderly patients with a hip fracture – A twenty year observation study
| Autor: | Manuela Jaindl, Florian M. Kovar, Oswald Wagner, Georg Endler |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty Prognostic factor Arthroplasty Replacement Hip Poison control Early death Haemoglobin levels Hemoglobins Basal (phylogenetics) Risk Factors Internal medicine Injury prevention Leukocytes medicine Humans Hospital Mortality Lymphocyte Count Aged General Environmental Science Aged 80 and over Hip fracture Hip Fractures business.industry Anemia Prognosis medicine.disease Surgery Hospitalization Austria Creatinine General Earth and Planetary Sciences Population study Female business |
| Zdroj: | Injury. 46:1018-1022 |
| ISSN: | 0020-1383 |
| DOI: | 10.1016/j.injury.2015.01.010 |
| Popis: | Introduction Hip fractures are a significant cause of mortality and morbidity in the elderly. This study investigated the relationship between initial haemoglobin (Hb) levels and a prognostic parameter for outcome in those patients. Patients and methods A total of 3595 consecutive patients with diagnosed hip fractures were included in our study (72.2% females). Anaemia was defined according to WHO criteria, with according subgroups mild, moderate and severe anaemia. Data collection was performed prospectively and statistical evaluation was performed retrospectively. Results Mean follow up in our study group was 11.2±0.3 months. The mean age of our study group was 78.5 years (SEM±0.2 years). To facilitate analysis, patients were divided in two groups: ≤84 years (60.1%) and ≥85 years (39.9%). Mortality n =439). In our study population lower Hb levels ad admission were associated with a markedly elevated short-term mortality. In a multivariate logistic regression model adjusted for age and sex, mild anaemia at admission caused a 1.5 (CI: 1.1–1.9), moderate anaemia a 2.6 (95 CI: 2.0–3.4), and severe anaemia a 3.6 (CI: 1.8–6.9) fold increase in three months mortality compared to patients without anaemia. Total lymphocyte count (1.2±0) did not show any differences between the subgroups. Conclusion Those findings in our study population with 3595 patients over a period of twenty years have proven that initial Hb levels are a useful and cost effective parameter to predict mortality in elderly patients with a hip fracture. This prognostic factor may help to increase the outcome of elderly patients with a hip fracture. |
| Databáze: | OpenAIRE |
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