| Autor: |
Giacomo Trapasso, Giovanna Mazzi, Beatriz Chícharo, Mattia Annatelli, Davide Dalla Torre, Fabio Aricò |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Organic process researchdevelopment. 26(10) |
| ISSN: |
1083-6160 |
| Popis: |
5-Hydroxymethylfurfural (HMF) is a bio-based platform chemical that can be used as a building block to produce several compounds with diverse applications. Even though HMF synthesis holds promise for a greener future, the current state of technology and the high production cost limit its competitiveness on an industrial scale. In this prospect, we have developed a multigram-scale procedure for HMF by reacting d-fructose with Purolite CT275DR-an acidic resin-in a dimethyl carbonate (DMC)/tetraethyl ammonium bromide (TEAB) biphasic system. Reactions performed in an autoclave for 2 h at 110 °C using up to 40 gram of d-fructose resulted in an overall HMF yield of 70%. HMF was purified by a custom-made procedure leading to ca 50% of the pure crystalline product; meanwhile, the residual HMF-rich oil was directly reduced to bis(hydroxymethyl)furan (BHMF). Green metrics and the Ecoscale algorithm were used to evaluate the sustainability of the herein-proposed procedure in comparison with previously reported works. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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