Factors affecting outcomes after supermicrosurgical lymphovenous anastomosis in a defined patient population

Autor:	Lukas Prantl, Gunther Felmerer, Christian D. Taeger, Adam Stepniewski, Eric Klingelhoefer, Karl Hesse
Rok vydání:	2019
Předmět:	Adult Male medicine.medical_specialty Complete data Physiology medicine.medical_treatment Context (language use) 030204 cardiovascular system & hematology 030218 nuclear medicine & medical imaging Lymphovenous anastomosis 03 medical and health sciences 0302 clinical medicine Physiology (medical) medicine Humans In patient Aged Lymphatic Vessels business.industry Anastomosis Surgical Hematology Microsurgery Middle Aged medicine.disease Surgery body regions Patient population Lymphedema medicine.anatomical_structure Treatment Outcome Upper limb Female Cardiology and Cardiovascular Medicine business Vascular Surgical Procedures
Zdroj:	Clinical hemorheology and microcirculation. 73(1)
ISSN:	1875-8622
Popis:	Background The optimal surgical treatment for lymphedema is still subject of intensive research. Therefore, it is vital to investigate what significance lymphovenous anastomosis (LVA) has in this context. Objective This study aims to determine the short- and long-term results as well as the most important factors that can improve outcomes after LVA. Methods This study includes a complete data set of 26 patients who received LVA for a therapy-resistant lymphedema. Patients were followed up for an average of 23 months. Results 50% of the patients reported a subjective improvement. Without conservative treatment after the operation the patients showed significant better results (100% vs. 40.9%, p = 0.030). The localization of lymphedema as well as the region of LVA had a significant influence. In patients with lymphedema affecting the entire leg, symptom improvement was significantly lower (35.3% vs. 77.8%, p = 0.039). Patients who received LVA in an upper limb show a significantly higher improvement in symptoms than patients who received LVA in a lower limb (100% vs. 30%, p = 0.021). Conclusions We identified factors with a significant influence on the outcome of patients after receiving LVA. Patients with early-stage upper extremity lymphedema seem to benefit most from this procedure.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bc293562318e035efdf96bc9547ab32 https://pubmed.ncbi.nlm.nih.gov/31561341 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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