The Spectrum of Constipation-Predominant Irritable Bowel Syndrome and Chronic Idiopathic Constipation: US Survey Assessing Symptoms, Care Seeking, and Disease Burden
| Autor: | Joel J. Heidelbaugh, Steve A Miller, William D. Chey, Margie Stelwagon, Elizabeth P. Shea |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male Pediatrics medicine.medical_specialty Time Factors Care seeking Health Behavior Efficiency Severity of Illness Index Cohort Studies Irritable Bowel Syndrome Chronic idiopathic constipation Cost of Illness Severity of illness medicine Humans Functional GI Disorders Irritable bowel syndrome Disease burden Aged Hepatology business.industry Incidence (epidemiology) Incidence Gastroenterology Middle Aged Patient Acceptance of Health Care medicine.disease Health Surveys United States Surgery Gastrointestinal Tract Chronic Disease Plecanatide Female business Constipation Cohort study |
| Zdroj: | The American Journal of Gastroenterology |
| ISSN: | 1572-0241 0002-9270 |
| Popis: | Introduction: The irritable bowel syndrome with constipation (IBS-C) and chronic idiopathic constipation (CIC) are associated with substantial symptom and disease burden. Although typically classified as distinct diseases, symptoms frequently overlap. Aim: The objective of this study was to characterize symptom and disease burden in IBS-C and CIC sufferers and examine a subset of CIC sufferers with abdominal symptoms. Methods: In a US population-based survey, respondents meeting the Rome III criteria for IBS-C or CIC rated symptom frequency and bothersomeness, missed work and disrupted productivity, and degree of obtaining and satisfaction with physician care. CIC respondents were analyzed in two subgroups: those with abdominal symptoms ≥once weekly (CIC-A) and those without (CIC-NA). Results: Of the 10,030 respondents, 328 met the criteria for IBS-C and 552 for CIC (363 CIC-A; 189 CIC-NA). All symptoms were significantly more frequent in IBS-C vs. CIC respondents (P |
| Databáze: | OpenAIRE |
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