Colorimetric Detection of Carcinogenic Alkylating Fumigants on Nylon-6 Nanofibrous Membrane. Part I: Investigation of 4-( p-Nitrobenzyl)pyridine as a 'New' Sensing Agent with Ultrahigh Sensitivity
| Autor: | Ho Ting Leung, Peixin Tang, Gang Sun |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Alkylating Agents
Polymers Pyridines Iodide Nanofibers 02 engineering and technology 01 natural sciences Analytical Chemistry chemistry.chemical_compound Bromide Pyridine Nucleophilic substitution Hydrocarbons Chlorinated Caprolactam Carcinogen chemistry.chemical_classification Detection limit 010405 organic chemistry 021001 nanoscience & nanotechnology Combinatorial chemistry Acute toxicity 0104 chemical sciences Allyl Compounds chemistry Solvents Colorimetry Gases 0210 nano-technology Methyl iodide |
| Zdroj: | Analytical chemistry. 90(24) |
| ISSN: | 1520-6882 |
| Popis: | Alkylating fumigants are widely used in agricultural production for the control of soil-borne pests, but the acute toxicity and carcinogenicity of these chemicals pose a health threat to farm workers, as well as residents. A nanofibrous membrane-based colorimetric sensor relying on the nucleophilic substitution reaction of 4-( p-nitrobenzyl)pyridine (NBP) is introduced for the convenient and portable detection of alkylating fumigants. Comparing with the traditional use of NBP in detecting alkylating agents, this sensor system achieves a parts per billion level detection sensitivity toward alkylating fumigant gases without a high-temperature incubation or the addition of extra bases. The mechanisms of the detection reaction and the detection sensitivities of different fumigants were studied with computational methods, and the results comprehensively prove the proposed optimized detection mechanisms. The detection limit of methyl iodide, methyl bromide, and 1,3-dichloropropene successfully reaches to the limiting exposure concentrations (PEL or REL) with a naked-eye detectable color difference within 5 min with a dynamic detection procedure. The designed sensing system is promising for a real-time monitoring of the air quality related to alkylating fumigants in the environment, especially in agricultural and industrial areas. |
| Databáze: | OpenAIRE |
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