Non-Aqueous Sol-Gel Synthesis of Ultra Small Persistent Luminescence Nanoparticles for Near-Infrared In Vivo Imaging
| Autor: | N. Lièvre, Sophie Richard, Guillaume Wang, Eliott Teston, Laurence Motte, Cyrille Richard, Yoann Lalatonne, Thomas Maldiney |
|---|---|
| Přispěvatelé: | Unité de Technologies Chimiques et Biologiques pour la Santé (UTCBS - UM 4 (UMR 8258 / U1022)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Chimie, Structures et Propriétés de Biomatériaux et d'Agents Thérapeutiques (CSPBAT), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Sorbonne Paris Nord, UPRES EA 3410, Université Paris 13 (UP13)-UFR SMBH, Laboratoire Matériaux et Phénomènes Quantiques (MPQ (UMR_7162)), Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP) |
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Luminescence
[SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging Nanoparticle Nanotechnology Photochemistry Catalysis Phase Transition NANOPROBE [SPI.MAT]Engineering Sciences [physics]/Materials Persistent luminescence In vivo CHEMISTRY LIVING CELLS Sol-gel Aqueous solution Spectroscopy Near-Infrared Chemistry Organic Chemistry IRON-OXIDE NANOPARTICLES Oxides General Chemistry RED Autofluorescence NANOCRYSTALS LIGHT Nanoparticles FUNCTIONALIZATION CONTRAST AGENTS Preclinical imaging BEHAVIOR |
| Zdroj: | Chemistry-A European Journal Chemistry-A European Journal, Wiley-VCH Verlag, 2015, 21 (20), pp.7350-7354. ⟨10.1002/chem.201406599⟩ |
| ISSN: | 0947-6539 1521-3765 |
| DOI: | 10.1002/chem.201406599⟩ |
| Popis: | International audience; Ultra-small ZnGa2O4:Cr3+ nanoparticles (6 nm) that exhibit near-infrared (NIR) persistent luminescence properties are synthesized by using a non-aqueous sol-gel method assisted by microwave irradiation. The nanoparticles are pegylated, leading to highly stable dispersions under physiological conditions. Preliminary in vivo studies show the high potential for these ultra-small ZnGa2O4:Cr3+ nanoparticles to be used as in vivo optical nanotools as they emit without the need for in situ excitation and, thus, avoid the autofluorescence of tissues. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text