Plasma protein pattern (Tiselius electrophoretic technique) in Cushing's syndrome
| Autor: | Lena A. Lewis, E. Perry McCullagh |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
medicine.medical_specialty
Pituitary gland Endocrinology Diabetes and Metabolism medicine.medical_treatment Clinical Biochemistry Biochemistry Cushing syndrome Endocrinology Internal medicine Acromegaly medicine Humans Cushing Syndrome biology business.industry Adrenalectomy Biochemistry (medical) Blood Proteins medicine.disease Blood proteins medicine.anatomical_structure Addison's disease biology.protein Antibody business Hormone |
| Zdroj: | The Journal of clinical endocrinology and metabolism. 7(8) |
| ISSN: | 0021-972X |
| Popis: | DOUGHERTY and White (7) reported an increase of the serum γ-globulin in rabbits following injection of large amounts of adrenal extract, and a release of γ-globulin antibody from lymphoid tissue following adrenal stimulation by adrenotrophic hormone, or following injection of adrenal extract (2). These observations suggested the question of what changes, if any, occur in the γ-globulin level of the plasma of patients with hyperadrenal function of the Cushing's syndrome type. METHODS A group of 9 patients proved by physical examination and pertinent laboratory findings to have Cushing's syndrome were studied. The results were contrasted with those obtained on patients with Addison's disease (5) and hypo-adrenal function of pituitary origin (6). In 8 of the patients with Cushing's syndrome, the plasma proteins were studied before treatment was instituted. Three of this group were observed for a period of as long as three years after therapy. One patient, no. 9, who had had a partial adrenalectomy and x-ray ... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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