Comparison of fragment analysis and immunohistochemistry to conventional Sanger sequencing for the detection of R132H and non-R132H IDH1 mutations in gliomas
| Autor: | Heubeck, E, Ludwig, N, Ebert, E, Kim, YY |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
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| Zdroj: | 60th Annual Meeting of the German Society for Neuropathology and Neuroanatomy (DGNN); 20150826-20150828; Berlin; DOC15dgnnP51 /20150825/ |
| DOI: | 10.3205/15dgnn75 |
| Popis: | Introduction: Both, primary and secondary glioblastomas are CNS tumors with a very poor prognosis. Both entities differ in their IDH1 mutational status. This mutation represents an early event in tumorigenesis of glioma and is a prognostic parameter. Objectives: To compare different detection methods[for full text, please go to the a.m. URL] 60th Annual Meeting of the German Society for Neuropathology and Neuroanatomy (DGNN) |
| Databáze: | OpenAIRE |
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