Giardiasis in children: molecular genotyping, growth and calprotectin levels

Autor: T.V. Sorokman, T. O. Bezruk, S.V. Sokolnyk, Natalia O. Popelyuk, Alexandra-Maria V. Popelyuk, V. V. Bezruk
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Archives of the Balkan Medical Union, Vol 54, Iss 3, Pp 522-531 (2019)
ISSN: 1584-9244
Popis: Introduction. Giardiasis is the most frequently reported human intestinal parasitic infection. The objective of the study was to investigate the frequency of giardiasis, carry out the genotyping, estimate the growth and determine the level of fecal calprotectin in children. Material and methods. 688 children aged 6-18 years were examined for Giardia duodenalis by direct microscopy. Two groups were formed: group I – children with a positive test for Giardia duodenalis (n = 90); group II – children with a negative test (n = 110). Genetic examination, anthropometry and fecal calprotectin (FC) evaluation were carried out in these children. Results. Out of the 688 children examined, 90 had a positive result (G. duodenalis (+)). The leading clinical feature of G. duodenalis infection (+) was abdominal pain, followed by nausea and diarrhea. The FC content in the feces of the group I was significantly higher (p
Databáze: OpenAIRE