Definition ofDrosophilahemocyte subsets by cell-type specific antigens
| Autor: | Éva Kurucz, János Zsámboki, Kinga Csorba, Péter Vilmos, Elisabeth Gateff, Robert Markus, Dan Hultmark, Balázs Váczi, Barbara Laurinyecz, István Andó |
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| Rok vydání: | 2007 |
| Předmět: |
Cell type
Hemocytes Blotting Western Biology General Biochemistry Genetics and Molecular Biology Flow cytometry Blood cell Mice Phagocytosis Antigen Precursor cell medicine Animals Compartment (development) Antigens Fluorescent Antibody Technique Indirect General Environmental Science Mice Inbred BALB C medicine.diagnostic_test Hematopoietic Tissue Antibodies Monoclonal Lamellocyte differentiation Flow Cytometry Molecular biology Cell Compartmentation medicine.anatomical_structure Neurology Drosophila Female |
| Zdroj: | Acta Biologica Hungarica. 58:95-111 |
| ISSN: | 1588-256X 0236-5383 |
| Popis: | We analyzed the heterogeneity of Drosophila hemocytes on the basis of the expression of cell-type specific antigens. The antigens characterize distinct subsets which partially overlap with those defined by morphological criteria. On the basis of the expression or the lack of expression of blood cell antigens the following hemocyte populations have been defined: crystal cells, plasmatocytes, lamellocytes and precursor cells. The expression of the antigens and thus the different cell types are developmentally regulated. The hemocytes are arranged in four main compartments: the circulating blood cells, the sessile tissue, the lymph glands and the posterior hematopoietic tissue. Each hemocyte compartment has a specific and characteristic composition of the various cell types. The described markers represent the first successful attempt to define hemocyte lineages by immunological markers in Drosophila and help to define morphologically, functionally, spatially and developmentally distinct subsets of hemocytes. |
| Databáze: | OpenAIRE |
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