Impact of mycoplasma pneumonia infection on urticaria: A nationwide, population-based retrospective cohort study in Taiwan
Autor: | Wei-Chu Yeh, Jing-Yang Huang, Hsing-Ju Wu, James Cheng-Chung Wei, Tung-Ming Chang, Huang-Hsi Chen, Su-Boon Yong |
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Rok vydání: | 2019 |
Předmět: |
Male
Bacterial Diseases Mycoplasma Pneumonia Urticaria Pulmonology Pathology and Laboratory Medicine Pediatrics 030207 dermatology & venereal diseases Mycoplasma 0302 clinical medicine Risk Factors immune system diseases Medicine and Health Sciences Mycoplasma Pneumoniae Longitudinal Studies Child skin and connective tissue diseases education.field_of_study Multidisciplinary Incidence Incidence (epidemiology) Hazard ratio Middle Aged Bacterial Pathogens Infectious Diseases Medical Microbiology Child Preschool Medicine Female Pathogens Pediatric Infections Research Article Cohort study Adult medicine.medical_specialty Adolescent Science Population Taiwan Mollicutes Dermatology Microbiology Young Adult 03 medical and health sciences Diagnostic Medicine Streptococcal Infections Internal medicine Pneumonia Mycoplasma parasitic diseases Upper Respiratory Tract Infections medicine Humans Propensity Score education Microbial Pathogens Proportional Hazards Models Retrospective Studies 030203 arthritis & rheumatology Bacteria Proportional hazards model business.industry Organisms Biology and Life Sciences Retrospective cohort study Pneumonia medicine.disease Relative risk Multivariate Analysis Respiratory Infections Mycoplasma pneumonia business |
Zdroj: | PLoS ONE, Vol 14, Iss 12, p e0226759 (2019) PLoS ONE |
ISSN: | 1932-6203 |
Popis: | Mycoplasma pneumonia (MP) infection might be pathogenically closely related to urticaria. This study is a nationwide population-based cohort study from 1997 to 2013, which investigated the association between MP infection and urticaria in Taiwan. A total of 1,175 patients were included for the study group, and 2,350 for the control group. Multivariate Cox regression analysis was performed to estimate the adjusted hazard ratio (aHR) for urticaria. Result showed that 254 patients with new-onset urticaria were involved in the study group and 465 incident cases in the control group. The incidence rates (per 100,000 person-months) of urticaria were 37.2 and 32.5 in the study and control groups, respectively. The relative risk is 1.1 (95% CI = 1.0–1.3) indicating no significant correlation between MP and urticaria. The multivariate analysis revealed that the risk of urticaria with MP infection (aHR = 1.1, P = 0.1058) had no statistically significance difference compared to the control group. However, the risk of urticaria in MP-infected patients aged between 20 and 59 years old was found to have increased (aHR = 1.6, 95% CI = 1.1–2.2) prior to a diagnosis. |
Databáze: | OpenAIRE |
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