Impact of mycoplasma pneumonia infection on urticaria: A nationwide, population-based retrospective cohort study in Taiwan

Autor: Wei-Chu Yeh, Jing-Yang Huang, Hsing-Ju Wu, James Cheng-Chung Wei, Tung-Ming Chang, Huang-Hsi Chen, Su-Boon Yong
Rok vydání: 2019
Předmět:
Male
Bacterial Diseases
Mycoplasma Pneumonia
Urticaria
Pulmonology
Pathology and Laboratory Medicine
Pediatrics
030207 dermatology & venereal diseases
Mycoplasma
0302 clinical medicine
Risk Factors
immune system diseases
Medicine and Health Sciences
Mycoplasma Pneumoniae
Longitudinal Studies
Child
skin and connective tissue diseases
education.field_of_study
Multidisciplinary
Incidence
Incidence (epidemiology)
Hazard ratio
Middle Aged
Bacterial Pathogens
Infectious Diseases
Medical Microbiology
Child
Preschool
Medicine
Female
Pathogens
Pediatric Infections
Research Article
Cohort study
Adult
medicine.medical_specialty
Adolescent
Science
Population
Taiwan
Mollicutes
Dermatology
Microbiology
Young Adult
03 medical and health sciences
Diagnostic Medicine
Streptococcal Infections
Internal medicine
Pneumonia
Mycoplasma
parasitic diseases
Upper Respiratory Tract Infections
medicine
Humans
Propensity Score
education
Microbial Pathogens
Proportional Hazards Models
Retrospective Studies
030203 arthritis & rheumatology
Bacteria
Proportional hazards model
business.industry
Organisms
Biology and Life Sciences
Retrospective cohort study
Pneumonia
medicine.disease
Relative risk
Multivariate Analysis
Respiratory Infections
Mycoplasma pneumonia
business
Zdroj: PLoS ONE, Vol 14, Iss 12, p e0226759 (2019)
PLoS ONE
ISSN: 1932-6203
Popis: Mycoplasma pneumonia (MP) infection might be pathogenically closely related to urticaria. This study is a nationwide population-based cohort study from 1997 to 2013, which investigated the association between MP infection and urticaria in Taiwan. A total of 1,175 patients were included for the study group, and 2,350 for the control group. Multivariate Cox regression analysis was performed to estimate the adjusted hazard ratio (aHR) for urticaria. Result showed that 254 patients with new-onset urticaria were involved in the study group and 465 incident cases in the control group. The incidence rates (per 100,000 person-months) of urticaria were 37.2 and 32.5 in the study and control groups, respectively. The relative risk is 1.1 (95% CI = 1.0–1.3) indicating no significant correlation between MP and urticaria. The multivariate analysis revealed that the risk of urticaria with MP infection (aHR = 1.1, P = 0.1058) had no statistically significance difference compared to the control group. However, the risk of urticaria in MP-infected patients aged between 20 and 59 years old was found to have increased (aHR = 1.6, 95% CI = 1.1–2.2) prior to a diagnosis.
Databáze: OpenAIRE
Externí odkaz: