Adherence to antiretroviral therapies in people with HIV infection: a qualitative approach from a narrative-based medicine study
| Autor: | Nicola Squillace, Stefano Zona, Aloisi, I Mazeu, Giovanni Guaraldi, Gabriella Orlando, A Tomasini, Rita Murri, M Bossola |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2008 |
| Předmět: |
Drug
medicine.medical_specialty business.industry media_common.quotation_subject Public health Human immunodeficiency virus (HIV) Public Health Environmental and Occupational Health HIV medicine.disease_cause Antiretroviral therapy adherence Infectious Diseases Family medicine Immunology Medicine Narrative business Adverse effect Viral load media_common |
| Popis: | Summary of results Twelve people with HIV were interviewed (four females).All interviewed people were taking HAART. Age range:38–65 years. Twenty-two hours of interviews wereobtained.Adherence to drugs was often reported as the crucial prob-lem in the daily management of the HIV infection. Amongreasons for suboptimal adherence several concepts wereelucidated through the interviews: 1) adverse eventsrelated to therapy are the main cause of suboptimal adher-ence; 2) particularly, alterations of body aspect due toabnormal adipose tissue redistribution (so-called lipodys-trophy) were identified as a strong factor leading to sub-optimal adherence; 3) reduction or modification of dailydosage of antiretroviral drugs were reported very fre-quently (11/12 interviewed people, 91.6%). They wereoften done without informing the physician. The mainreason for doing a reduction or modification of daily dos-age was an adverse event. People often believe that physi-cians could not be aware of these modifications since noimmediate change in viral load is detectable; 4) subopti-mal adherence to drugs was correlated to a poor belief indrug efficacy; 5) the social representation of the drug ofteninfluences adherence; and 6) the drug experience often isa reminder of the psychological experience of the illness. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|