A1 asynchrony, a potential risk factor for the rupture of anterior communicating artery aneurysms: A computational fluid dynamics study
| Autor: | Juan Pou, Pedro Miguel González-Vargas, Cesáreo Conde Alonso, Antonio Riveiro Rodríguez, José Luis Thenier-Villa, Raúl Alejandro Galárraga Campoverde, Adolfo Ramón De La Lama Zaragoza, Miguel Gelabert-González, Lourdes Calero-Félix, Rosa María Martínez-Rolán |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Anterior Cerebral Artery Computed Tomography Angiography Hemodynamics Aneurysm Ruptured Computational fluid dynamics 03 medical and health sciences 0302 clinical medicine Aneurysm Risk Factors Internal medicine medicine.artery medicine Shear stress Humans Computer Simulation Pulse Aged business.industry Intracranial Aneurysm Blood flow Middle Aged Subarachnoid Hemorrhage medicine.disease Asynchrony (computer programming) Anterior communicating artery medicine.anatomical_structure Pulsatile Flow Hemorheology Hydrodynamics Cardiology Female Surgery Neurology (clinical) business Blood Flow Velocity 030217 neurology & neurosurgery Artery |
| Zdroj: | Neurocirugía. 30:207-214 |
| ISSN: | 1130-1473 |
| DOI: | 10.1016/j.neucir.2019.04.002 |
| Popis: | Introduction and objectives: The anterior communicating complex is one the most common locations for aneurysm development. It receives blood from both carotid circulations and the effect of synchrony on the arrival of blood flow has not been previously studied. The objective of this study was to compare the asynchrony conditions of the A1 pulse and its effects on the haemodynamic conditions of anterior communicating artery (ACoA) aneurysms. Materials and methods: From 2008 to 2017, 54 anterior communicating artery aneurysms treated at our centre were included in the study. Computational fluid dynamics (CFD) techniques were employed and simulations consisted of complete conditions of synchrony and introducing a delay of 0.2 s in the non-dominant A1 artery. Time-averaged wall shear stress (TAWSS), low shear area (LSA), A1 diameter and ACoA angles were measured. Results: The difference in the LSA in conditions of synchrony and asynchrony resulted in a broad range of positive and negative values. The symmetry index (p = 0.04) and A1/A2 angle on the dominant artery (p = 0.04) were associated with changes in LSA. Conclusions: In asynchrony, LSA increased in the absence of A1 asymmetry and low A1/A2 angles, potentially increasing the risk of aneurysm rupture in this location. |
| Databáze: | OpenAIRE |
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