Challenging management of gingival squamous cell carcinoma: a 10 years single-center retrospective study on Northern-Italian patients
| Autor: | Paolo-Giacomo Arduino, Mario Carbone, Alessio Gambino, Davide Conrotto, Roberto Broccoletti, Alessandra Macciotta, Marco Cabras, Filippo Cannarsa |
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| Rok vydání: | 2020 |
| Předmět: |
Gingival Squamous Cell Carcinoma
medicine.medical_specialty Wilcoxon signed-rank test anti-inflammatory drugs Single Center corticosteroids severe odontogenic infection Internal medicine medicine Humans Stage (cooking) General Dentistry Survival rate Survival analysis UNESCO:CIENCIAS MÉDICAS Neoplasm Staging Retrospective Studies Oral Medicine and Pathology business.industry Research Clinical course Retrospective cohort study Prognosis Survival Rate Otorhinolaryngology Italy Head and Neck Neoplasms Carcinoma Squamous Cell Surgery business |
| Zdroj: | Medicina Oral, Patología Oral y Cirugía Bucal Arduino, PG., Carbone, M., Gambino, A., Cabras, M., Cannarsa, F., Macciotta, A., Conrotto, D., & Broccoletti, R. (2021). Challenging management of gingival squamous cell carcinoma: a 10 years single-center retrospective study on Northern-Italian patients. En Medicina Oral Patología Oral y Cirugia Bucal (pp. e21-e27). Medicina Oral, S.L. https://doi.org/10.4317/medoral.23913 |
| ISSN: | 1698-6946 |
| Popis: | Background Aim of this study was to describe the outcome of patients with gingival squamous cell carcinoma (GSCC), and to recognize aspects affecting clinical course and to consider survival rate. Material and Methods The case records of patients, over a 10-year period, were retrospectively examined. Differences in distribution of the potential risk factors by prognosis were investigated through non-parametrical tests (Wilcoxon Rank-Sum and Fisher’s Exact). Survival curves for age, therapy and stage were built by the Kaplan-Meier method and compared with Log-Rank test. Results 79 patients were analysed. Significant increase in mortality for patients older than 77 and for those with advanced stages was found. Cumulative survival rate 5 years after the diagnosis was 43%, while at 10 years was of 11%. Conclusions With a statistical relationship between age and tumour stage with survival rates, and 70% of GSCC cases identified as stage IV, early GSCC diagnosis remains challenging. Key words:Gingival cancer, clinical appearance, treatment, retrospective study. |
| Databáze: | OpenAIRE |
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