Factors influencing serum 25-hydroxivitamin D levels and other bone metabolism parameters in healthy older women
| Autor: | Emine Meral Inelmen, Giuseppe Sergi, Alessandra Coin, Egle Perissinotto, Nicola Veronese, M. De Rui, Francesco Bolzetta, Enzo Manzato, Linda Berton, S. Carraro, F. Miotto, Caterina Trevisan |
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| Přispěvatelé: | Trevisan, C., Veronese, N., Berton, L., Carraro, S., Bolzetta, F., de Rui, M., Miotto, F., Inelmen, E.M., Coin, A., Perissinotto, E., Manzato, E., Sergi, G. |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Bone density Medicine (miscellaneous) 030209 endocrinology & metabolism 25-hydroxyvitamin D bone metabolism dietary vitamin D intake elderly fat mass Nutrition and Dietetics Geriatrics and Gerontology NO Bone remodeling 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Internal medicine medicine Vitamin D and neurology Femoral neck Bone mineral Hyperparathyroidism 030109 nutrition & dietetics business.industry medicine.disease medicine.anatomical_structure Endocrinology chemistry 25-hydroxyvitamin D dietary vitamin D intake fat mass bone metabolism elderly Calcifediol Secondary hyperparathyroidism business |
| Zdroj: | The journal of nutrition, health & aging. 21:131-135 |
| ISSN: | 1760-4788 1279-7707 |
| DOI: | 10.1007/s12603-016-0746-6 |
| Popis: | Objective: Older women have frequently low serum 25-hydroxivitamin D (25[OH]D) concentrations, high parathormone (PTH) levels and low bone mineral density (BMD) values. Endogenous synthesis, dietary habits, sunlight exposure and fat-mass-mediated storage may influence 25(OH)D levels and bone metabolism, but the relevance of these factors in the elderly has yet to be fully elucidated. We aimed to investigate the influence of dietary vitamin D intake and fat mass on serum 25(OH)D levels and bone metabolism in older women. Design: Cross-sectional. Setting: Community. Participants: 218 fit older women attending a biweekly mild fitness program. Measurements: Dietary habits was investigated through a 3-day record questionnaire. Serum 25(OH)D and intact parathormone (PTH) concentrations were measured by radioimmunoassay and by a 2-step immunoradiometric assay, respectively. BMD and body composition were estimated using dualenergy X-ray absorptiometry with fan-beam technology. Results: Only fat mass showed a significant negative association with 25(OH)D (β=-3.76, p |
| Databáze: | OpenAIRE |
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