Delayed Viral Clearance of Chronic Hepatitis C in Patients after Treatment Failure

Autor:	Yang Hyun Baek, Jin Seok Jang, Sang Young Han, Su Young Kim, Jong-Hoon Lee, Seok Reyol Choi, Su Hyun Cho, Sung Wook Lee, Myung Hwan Roh
Rok vydání:	2011
Předmět:	medicine.medical_specialty Hepatology business.industry Standard treatment Hepatitis C virus Gastroenterology Case Report medicine.disease_cause Virology Discontinuation Virological response Chronic hepatitis Internal medicine Genotype Medicine In patient business After treatment
Zdroj:	Gut and Liver. 5:110-114
ISSN:	2005-1212 1976-2283
DOI:	10.5009/gnl.2011.5.1.110
Popis:	Hepatitis C virus (HCV) infection usually progresses to chronic hepatitis, with rare cases of spontaneous viral eradication. We present herein four cases involving patients that were initially declared to have failed to respond to treatments, based on the presence of HCV RNA that was still detectable after completion of the standard treatment for chronic hepatitis C with genotype 2. However, the HCV RNA became undetectable, with a delayed response, after discontinuation of therapy. Two of the four patients were diagnosed as treatment failures after extended treatment, and the other two received no further treatment after the standard treatment. All four patients maintained a sustained virological response during the periodic follow-up after delayed viral clearance.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b70c779d16c4fd8391f51f135f8c9f2 https://doi.org/10.5009/gnl.2011.5.1.110 Zobrazit plný text záznamu