Grazing incidence X-ray diffraction of highly aligned phospholipid membranes containing the antimicrobial peptide magainin 2
| Autor: | B. Bechinger, C. Münster, Tim Salditt, J. Lu |
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| Rok vydání: | 2000 |
| Předmět: |
Models
Molecular food.ingredient Protein Conformation Antimicrobial peptides Lipid Bilayers Molecular Sequence Data Biophysics Phospholipid Molecular Conformation Peptide Xenopus Proteins Magainins Lecithin chemistry.chemical_compound food Anti-Infective Agents X-Ray Diffraction Amphiphile Amino Acid Sequence Lipid bilayer chemistry.chemical_classification Chemistry Magainin General Medicine Crystallography Membrane lipids (amino acids peptides and proteins) Dimyristoylphosphatidylcholine Peptides Antimicrobial Cationic Peptides |
| Zdroj: | European biophysics journal : EBJ. 28(8) |
| ISSN: | 0175-7571 |
| Popis: | We present the first study of grazing incidence X-ray diffraction on a model system of phospholipid membranes and antimicrobial peptides. For this purpose, highly oriented multilamellar samples have been prepared on solid substrates. By this technique, the short-range order of the lipid chains in the fluid L(alpha) phase can be investigated quantitatively, including not only the mean distance between acyl chains, but also the associated correlation length. The short-range order in lecithin is found to be severely affected by the amphiphilic peptide magainin 2. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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