Characteristics of Lipids Imbalance in Patients with Tick‐Borne Encephalitis

Autor:	G. A. Nevinsky, N. A. Tuzikova, F. V. Tuzikov, B. M. Doronin, Valentina N. Buneva, N. V. Garmashova, O. B. Tyshkevich
Rok vydání:	2004
Předmět:	Chemistry Multiple sclerosis Tick-borne encephalitis General Medicine medicine.disease Lipids Biochemistry Scattering radiation Healthy individuals Immunology Blood plasma Genetics medicine Humans Scattering Radiation Molecular Medicine In patient Factor Analysis Statistical Encephalitis Tick-Borne Encephalitis Hypolipoproteinemia
Zdroj:	Nucleosides, Nucleotides and Nucleic Acids. 23:1003-1007
ISSN:	1532-2335 1525-7770
DOI:	10.1081/ncn-200026055
Popis:	Using a novel approach, we have analyzed 30 parameters characterizing detailed spectrum and fractional content of LPs in plasma of patients with tick-borne encephalitis (TBE). The blood plasma of all TBE patients (30 patients), as compared with that of healthy individuals (120 patients), is characterized by decreased concentrations of many LP subfractions and of the total concentration of all plasma LPs (hypolipoproteinemia). The observed difference in some parameters was statistically significant. Using computer-assisted factor analysis, we have shown that according to these 30 parameters TBE patients are similar to patients with multiple sclerosis and systemic lupus erythematosus. The results provide grounds for using data on blood plasma LPs as additional criteria for diagnosis of TBE.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b662a813704242240bb32d6132def60 https://doi.org/10.1081/ncn-200026055 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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