Carbapenem-resistant Pseudomonas aeruginosa: factors influencing multidrug-resistant acquisition in non-critically ill patients
| Autor: | Carmen Peña, Miquel Pujol, Mercedes Sora, Javier Ariza, Francisco Gudiol, Angela Domínguez, Cristina Suárez, Fe Tubau |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Microbiology (medical)
Male medicine.medical_specialty medicine.drug_class Antibiotics Biology medicine.disease_cause Microbiology Medical microbiology Catheters Indwelling Risk Factors Internal medicine Drug Resistance Multiple Bacterial medicine Humans Pseudomonas Infections Antibacterial agent Aged Aged 80 and over Pseudomonas aeruginosa General Medicine Odds ratio Middle Aged Hospitals Anti-Bacterial Agents Multiple drug resistance Infectious Diseases Carbapenems Colistin Female Cohort study medicine.drug Fluoroquinolones |
| Zdroj: | European journal of clinical microbiologyinfectious diseases : official publication of the European Society of Clinical Microbiology. 28(5) |
| ISSN: | 1435-4373 |
| Popis: | A cohort study was carried out on hospitalized adult non-critically ill patients (January 2003–December 2004) to identify factors associated with the acquisition of multidrug-resistant Pseudomonas aeruginosa (MDR-PA). A total of 246 non-critically patients were included, 162 (66%) who revealed MDR-PA in the first isolate and 84 (34%) who had carbapenem-resistant P. aeruginosa (CR-PA) isolates. Multivariate analysis identified nosocomial acquisition (odds ratio [OR] 2.7, 95% confidence interval [CI] 1.1–6.3), urinary catheter (OR 2.1, 95%CI 1.1–4.3), and the prior use of fluoroquinolones (OR 2.6, 95%CI 1.0–6.7) as independent risk factors associated with MDR-PA acquisition. Our results show that antibiotics, most notably, fluoroquinolones, may play a major role in the emergence of MDR-PA. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink