Production of acute rheumatic-like heart lesions in mice
| Autor: | F. J. Moore, G. K. Ridge, R. W. Huntington, E. M. Hall, G. C. Griffith, R. G. Knowles |
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| Rok vydání: | 2010 |
| Předmět: |
Pathology
medicine.medical_specialty Heart Diseases business.industry Physiology macromolecular substances medicine.disease General Biochemistry Genetics and Molecular Biology Mice medicine.anatomical_structure Rheumatic Diseases medicine Rheumatic fever Animals Rheumatic Fever business Anaphylaxis Sensitization Egg white |
| Zdroj: | Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 65(1) |
| ISSN: | 0037-9727 |
| Popis: | SummaryAcute rheumatic-like heart lesions have been produced in mice by parenteral injection of egg white on repeated occasions. Minimal lesions may also occur in untreated mice, possibly as a result of spontaneous sensitization and shocking by natural contact with protein. There was no apparent relation between the severity of clinical anaphylaxis and the severity of the pathologic changes in the heart. |
| Databáze: | OpenAIRE |
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