Micro-hotspots of Risk in Urban Cholera Epidemics

Autor: Enrico Bertuzzo, Francisco Javier Luquero Alcalde, Louis Albert Massing, Jerome Leglise, Flavio Finger, Mohammad Ali, David Olson, Brahima Toure, Henrik Salje, Bansaga Saga, Amelie Cardon, Maya Allan, Romain Ramazani, Justin Lessler, Ngandwe Adalbert, Klaudia Porten, Nathan Naibei Mbaïbardoum, Andrew S. Azman
Jazyk: angličtina
Rok vydání: 2018
Předmět:
DOI: 10.1101/248476
Popis: Targeted interventions have been delivered to neighbors of cholera cases in epidemic responses in Haiti and Africa despite little evidence supporting impact. Using data from urban epidemics in Chad and D.R. Congo we estimate the size and extent of spatiotemporal zones of increased cholera risk around cases. In both cities, we found zones of increased risk of at least 200-meters during the 5-days immediately following case presentation to a clinic. Risk was highest for those living closest to cases and diminished in time and space similarly across settings. These results provide a rational basis for targeting interventions, if delivered rapidly.
Databáze: OpenAIRE