Toxoplasma gondii: seroprevalence and associated risk factors among preschool-aged children in Osun State, Nigeria
| Autor: | Vincent P. Gyang, O. P. Akinwale, Chia Kwung Fan, Bolaji O. Badejoko, Timothy Nwafor, Ting Wu Chuang, Yueh Lun Lee, Tsung Han Wu, Emmanuel Henry, O.A. Sowemimo, S. O. Asaolu |
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| Rok vydání: | 2018 |
| Předmět: |
Male
0301 basic medicine Meat 030106 microbiology 030231 tropical medicine Antibodies Protozoan Nigeria Enzyme-Linked Immunosorbent Assay Soil 03 medical and health sciences 0302 clinical medicine Risk Factors Seroepidemiologic Studies Statistical significance Environmental health parasitic diseases Animals Humans Medicine Seroprevalence Policy Making biology business.industry Transmission (medicine) Significant difference Public Health Environmental and Occupational Health Infant Water Toxoplasma gondii General Medicine biology.organism_classification medicine.disease Serum samples Toxoplasmosis Cross-Sectional Studies Infectious Diseases Child Preschool Cats Female Parasitology Disease prevention business Toxoplasma |
| Zdroj: | Transactions of The Royal Society of Tropical Medicine and Hygiene. |
| ISSN: | 1878-3503 0035-9203 |
| Popis: | Background Toxoplasma gondii is an ubiquitous apicomplexan parasite, which causes toxoplasmosis in animals and humans worldwide. However, little is known about T. gondii infection among preschool-aged children in Nigeria. Methods A cross-sectional study of 272 preschool children aged 2.25±1.09 years from four communities (Edunabon, Erin-Ijesha, Ijebu-jesa and Ile-Ife) in Osun State, Nigeria was conducted between January and July 2016, and the demographic data was obtained via questionnaires. Antibody titres against T. gondii of serum samples were assessed by ELISA. Results The overall seroprevalence of T. gondii infection was 6.9% (19/272). There was no significant difference in seroprevalence of T. gondii infection between boys (7.04%; 10/142) and girls (6.92%; 9/130; p=0.97). No associations were found between age, gender, parental educational level, occupation and religion, and T. gondii seropositivity. None showed statistical significance between the risk factors tested after multivariate adjustment; nevertheless, residing in Ijebu-jesa community was shown to be associated with an increased risk of infection (p=0.04). Conclusion This is the first report of T. gondii infection among preschool children in Nigeria. Prevalence studies such as this could help in the development of strategies for the future for disease prevention and control of T. gondii transmission. |
| Databáze: | OpenAIRE |
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