DuoStim: a new option for fertility preservation for a woman with Turner syndrome

Autor: Mineto Morita, Yusuke Fukuda, Yukiko Katagiri, Yuko Tamaki, Ayako Oji, Ayumu Ito
Rok vydání: 2020
Předmět:
Infertility
endocrine system
medicine.medical_specialty
Menotropins
endocrine system diseases
Endocrinology
Diabetes and Metabolism
Gonadal dysgenesis
Oocyte Retrieval
Turner Syndrome
030209 endocrinology & metabolism
Primary Ovarian Insufficiency
Buserelin
Gonadotropin-Releasing Hormone
03 medical and health sciences
Young Adult
0302 clinical medicine
Endocrinology
Hypergonadotropic hypogonadism
Ovulation Induction
Turner syndrome
17 alpha-Hydroxyprogesterone Caproate
Medicine
Humans
Fertility preservation
Ovarian Reserve
Menstruation Disturbances
Oncofertility
Gynecology
Cryopreservation
030219 obstetrics & reproductive medicine
business.industry
Mosaicism
Obstetrics and Gynecology
Fertility Preservation
Fertility Agents
Female
medicine.disease
female genital diseases and pregnancy complications
Premature ovarian failure
Dydrogesterone
Female
Abnormality
business
Infertility
Female
Zdroj: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. 36(12)
ISSN: 1473-0766
Popis: Turner syndrome (TS) is associated with hypergonadotropic hypogonadism due to gonadal dysgenesis, which results in premature ovarian failure and subsequent infertility. Therefore, counseling and evaluation for fertility preservation are required as early as possible for women with TS.A 23-year-old unmarried woman with mosaic TS (45, X [4/30] 46, XX [26/30]) presented to the pediatric department of our hospital for fertility counseling; she was accompanied by her mother. She was referred to the reproduction center of our hospital for ovarian reserve assessment and counseling regarding fertility preservation. We decided to retrieve oocytes using DuoStim as the controlled ovarian stimulation protocol. During the first and second oocyte retrievals, a total of 17 (9 and 8, respectively) mature metaphase II oocytes were cryopreserved.DuoStim may be a useful option for fertility preservation for women with TS and reduced ovarian reserve. This new strategy may obtain the required number of oocytes in the shortest time and preserve the future fertility of women with TS.
Databáze: OpenAIRE
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