Glycemic control and complications of type 1 diabetes among children in Tanzania
| Autor: | A. B. M. Swai, Edna Majaliwa, D. Jasem, Johnny Ludvigsson, S. Najem, K. Ramaiya |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Pediatrics
medicine.medical_specialty Medicin och hälsovetenskap HbA1c Complications Endocrinology Diabetes and Metabolism 030209 endocrinology & metabolism Medical and Health Sciences Tanzania lcsh:Diseases of the endocrine glands. Clinical endocrinology Nephropathy 03 medical and health sciences 0302 clinical medicine Endocrinology Diabetes mellitus Medicine 030212 general & internal medicine Young adult Retinopathy Glycemic Type 1 diabetes lcsh:RC648-665 biology business.industry Retrospective cohort study medicine.disease biology.organism_classification Neuropathy business Research Paper |
| Zdroj: | Journal of Clinical & Translational Endocrinology, Vol 23, Iss, Pp 100245-(2021) Journal of Clinical & Translational Endocrinology |
| ISSN: | 2214-6237 |
| Popis: | Introduction Knowledge on Type 1 Diabetes (T1D) in sub-Saharan Africa is scarce. This study aimed at assessing microvascular complications of Type 1 diabetes in young patients. Method A retrospective study based on medical recordings from 2010–2016 was done. 604 children and young adults with T1D were recruited from five hospitals with pediatric diabetes clinics. 559 patients aged 2–35 years with known date of birth were included. Clinical data on retinopathy and neuropathy were analyzed. There was no information on renal function/ nephropathy. Results Most data were missing. There was documentation on HbA1C, plasma glucose and complications in less than half of the patient files. Of those with registered HbA1c values (42.2%), 36% had HbA1c > 12.5%. There was high prevalence of retinopathy (21.5%) and neuropathy (29.4%) in spite of short mean duration of diabetes (6.2 ± 4.1 years). Conclusion Many patients with T1D in Tanzania have poor metabolic control. Microvascular complications are common already after a short duration of diabetes, but the results have to be interpreted with great caution because of study limitations. Better pediatric diabetes care as well as increased awareness of diabetes is needed. Studies in resource-poor countries need careful planning, if possible with prospective design. |
| Databáze: | OpenAIRE |
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