Asymmetric induction by the (S)-1-phenylethyl group in intramolecular nitrile imine cycloadditions giving enantiopure 3,3a-dihydro-pyrazolo[1,5-a][1,4]benzodiazepine-4(6H)-ones

Autor:	Tullio Pilati, Giorgio Molteni, Gaetano Zecchi, Gianluigi Casalone, Luisa Garanti, Gianluigi Broggini
Rok vydání:	1999
Předmět:	Benzodiazepine Nitrile Stereochemistry medicine.drug_class Organic Chemistry Imine Asymmetric induction Catalysis Inorganic Chemistry chemistry.chemical_compound Enantiopure drug chemistry Group (periodic table) Intramolecular force medicine Stereoselectivity Physical and Theoretical Chemistry
Zdroj:	Tetrahedron: Asymmetry. 10:4447-4454
ISSN:	0957-4166
DOI:	10.1016/s0957-4166(99)00493-0
Popis:	Stereoselective intramolecular cycloadditions of homochiral nitrile imines 5 are described as a fruitful source of enantiopure 3,3a-dihydro-pyrazolo[1,5-a][1,4]benzodiazepine-4(6H)-ones 6 and 7.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b4641d2c4b87a7039d030bc512c6e0c https://doi.org/10.1016/s0957-4166(99)00493-0 Zobrazit plný text záznamu Full Text from ScienceDirect