| Popis: |
Orodispersible films have been identified as an alternative approach to conventional dosage forms. The films are considered to be convenient to swallow, self-administrable, and fast dissolving dosage form, out of that it has a versatile platform for drug delivery. This delivery system has been used for both systemic and local action through several routes such as oral, buccal, sublingual, ocular, and transdermal routes. The sublingual and buccal delivery of a drug through thin film has the potential to improve the onset of action, lower the dosing, and enhance the efficacy and safety profile of the medicament. The films are polymeric matrices designed to be mucoadhesive properties and usually formulated with permeability enhancers to improve bioavailability. Among all fast release dosage forms, orodispersible films are successful to attract pharmaceutical industry due to ease of formulation and extension patent life. Films are popular in patients too because of quick onset and user-friendliness of the dosage form. Films rapidly hydrate and then disintegrate and/or dissolve to release the medication. This article provides a framework for further discussion and scientific work to improve orodispersible films. |
