Assessment of insecticidal effects and selectivity of CAPA‐PK peptide analogues against the peach‐potato aphid and four beneficial insects following topical exposure
| Autor: | Julian A. T. Dow, Pengyu Chen, Qun Yang, Aniruddha A. Pandit, Clauvis Nji Tizi Taning, Mohamad Hamshou, Guy Smagghe, Kristof De Schutter, Shireen A. Davies, Ronald J. Nachman, Shun-Hua Gui |
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| Rok vydání: | 2020 |
| Předmět: |
0106 biological sciences
Insecticides Aphid Adalia bipunctata Insecta business.industry Pest control General Medicine Biology biology.organism_classification 01 natural sciences Nasonia vitripennis Toxicology 010602 entomology Aphids Insect Science Animals Beneficial insects Red flour beetle Myzus persicae Peptides business Agronomy and Crop Science Chrysoperla carnea 010606 plant biology & botany |
| Zdroj: | Pest Management Science. 76:3451-3458 |
| ISSN: | 1526-4998 1526-498X |
| Popis: | Background Insect Capability neuropeptides (CAP2b/CAPA-PKs) play a critical role in modulating different physiologies and behavior in insects. In a previous proof-of-concept study, the CAP2b analogues 1895 (2Abf-Suc-FGPRLamide) and 2129 (2Abf-Suc-ATPRIamide) were reported to reduce aphid fitness when administered by injection. In the current study, the insecticidal efficacy of 1895 and 2129 on the peach potato aphid Myzus persicae was analyzed by topical application, simulating a spray application scenario in the field. Additionally, the selectivity of the tested analogues was evaluated against a selection of beneficial insects, namely three natural enemies (Adalia bipunctata, Chrysoperla carnea and Nasonia vitripennis) and a pollinator (Bombus terrestris). Results Within 3-5 days post topical exposure of aphids to 1895, higher mortality (33%) was observed, as was the case for the treatment with 2129 (17%) and the mixture of 1895 + 2129 (47%) compared to the control (3%). 1895 and the mix 1895 + 2129 showed the strongest and comparable insecticidal effects. Additionally, surviving aphids treated with 1895 showed a reduction in total lifetime reproduction (GRR) of 30%, 19% with 2129 and 39% with the mix 1895 + 2129. Of interest from a biosafety perspective is that by using the same delivery method and dose, no significant effects on survival, weight increase and food intake was observed for the representative natural enemies and the pollinator. Conclusion This study highlights the potential of exploiting CAP2b analogues such as 1895 (core structure FGPRL) as aphicides. Additionally, the CAP2b analogues used in this study were selective as they showed no effects when applied on four representative beneficial insects. |
| Databáze: | OpenAIRE |
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