Microbial dehalogenation
| Autor: | Dick B Janssen, Jantien E Oppentocht, Gerrit J Poelarends |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
inorganic chemicals
HALOALKANE DEHALOGENASE ENZYME Bacteria Hydrocarbons Halogenated Hydrolases Biomedical Engineering L-2-HALOACID DEHALOGENASE Bioengineering DESULFITOBACTERIUM DEHALOGENANS DEGRADATION SP Bacterial Physiological Phenomena GENE Aerobiosis Catalysis Biodegradation Environmental REDUCTIVE DEHALOGENASE CRYSTAL-STRUCTURES Anaerobiosis SPHINGOMONAS-PAUCIMOBILIS UT26 Biotechnology |
| Zdroj: | Current Opinion in Biotechnology. 12:254-258 |
| ISSN: | 0958-1669 |
| DOI: | 10.1016/s0958-1669(00)00208-1 |
| Popis: | Novel dehalogenases have been identified recently in various bacteria that utilise halogenated substrates. X-ray studies and sequence analysis have revealed insight into the molecular mechanisms of hydrolytic dehalogenases. Furthermore, genetic and biochemical studies have indicated that reductive dehalogenases are extra-cytoplasmic corrinoid-containing iron-sulphur proteins. Sequence analysis and mutagenesis studies indicate that several dehalogenases are homologous to enzymes that carry out transformations on non-halogenated substrates. |
| Databáze: | OpenAIRE |
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