Estimation of the prevalence of asymptomatic pancreatic cysts in the population of San Marino
| Autor: | Giulio Cipolla d'Abruzzo, Raffaele Lombardi, Marilyn Guidi, Nicola Zanini, Giorgio Pazzaglini, Marino Gatti, Elio Jovine, Giovanni Vitullo, Giorgia Chiaruzzi, Elia Smerieri, Marco Giordano, Giovanni Landolfo, Paolo Piva, Fiorella De Luca |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Pediatrics Adolescent Endocrinology Diabetes and Metabolism Population Contrast Media Asymptomatic Young Adult Sex Factors Neoplasms San Marino Epidemiology medicine Image Processing Computer-Assisted Prevalence Humans Cyst Young adult education Aged Aged 80 and over education.field_of_study Hepatology business.industry Gastroenterology Age Factors Middle Aged medicine.disease medicine.anatomical_structure Female Radiology medicine.symptom Pancreatic cysts Pancreatic Cyst Pancreas business Tomography X-Ray Computed |
| Zdroj: | Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]. 15(4) |
| ISSN: | 1424-3911 |
| Popis: | There has been a dramatic increase in the number of pancreatic cystic lesions observed in the past two decades but data regarding the prevalence of cysts in the general population are lacking.All the individuals who undergo CT at the San Marino State Hospital are residents of the Republic of San Marino; their demographic distribution is available and precise. CT scans carried out over 1 year at the State Hospital were reviewed for asymptomatic pancreatic cysts.1061 relevant CT scans were carried out on 814 patients; 762 individuals were eligible for the study and 650 patients underwent contrast-enhanced CT. Thirty-five patients had at least one cyst at contrast-enhanced CT (5.4%). The prevalence of cysts increased with increasing age up to 13.4% (95% CI 6.6-20) in individuals 80-89 years of age (p .001). Cyst prevalence was significantly higher in patients who underwent CT for malignancy (p = .038) but this difference was no longer significant in multivariate analysis. The odds of a cyst being present increased by 1.05 (95% CI 1.02-1.09) for each increasing year of age (p = .002). Approximately a quarter of the patients with cysts died within 1 year after CT from non pancreas-related disease. The estimated standardized age-adjusted cyst prevalence is 2194 per 100,000 people.The likelihood of having a pancreatic cyst correlates with increasing age, not with the presence of extra-pancreatic malignancies. The estimated prevalence of CT-detectable asymptomatic pancreatic cysts in the general population is 2.2%. |
| Databáze: | OpenAIRE |
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