Macroglossia secondary to lisinopril-induced acute angioedema

Autor: Andrew Read-Fuller, Colten Ducote, Matthew J. Kesterke, Ritesh Bhattacharjee, Likith V. Reddy
Rok vydání: 2019
Předmět:
Zdroj: Baylor University Medical Center Proceedings. 32:70-72
ISSN: 1525-3252
0899-8280
DOI: 10.1080/08998280.2018.1540736
Popis: Presented here are two cases of acute acquired macroglossia in adults caused by angioedema resulting from a reaction to angiotensin-converting enzyme inhibitors (ACEIs). Angioedema can be caused by a variety of factors, but ACEIs are the most common precipitating factor. Symptoms such as swelling of the lips, face, tongue, and throat can lead to life-threatening airway compromise. Early management of acute angioedema and macroglossia includes antihistamines, steroids, and occasionally epinephrine, yet a small percentage of patients progress toward airway obstruction and will require intubation. Edema within the lips, face, and throat usually subsides within a week, but the tongue can remain edematous for prolonged periods if biting trauma occurs. If the patient’s macroglossia does not resolve in a reasonable amount of time, a partial glossectomy may be indicated.
Databáze: OpenAIRE